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BMC Clinical Pharmacology

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  1. Content type: Research article

    Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ f...

    Authors: Manu Shankar-Hari, Peter S Kruger, Stefania Di Gangi, Damon C Scales, Gavin D Perkins, Danny F McAuley and Marius Terblanche

    Citation: BMC Clinical Pharmacology 2012 12:13

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  2. Content type: Research article

    Observational data are increasingly being used for pharmacoepidemiological, health services and clinical effectiveness research. Since pharmacies first introduced low-cost prescription programs (LCPP), researc...

    Authors: Vivienne J Zhu, Anne Belsito, Wanzhu Tu and J Marc Overhage

    Citation: BMC Clinical Pharmacology 2012 12:12

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  3. Content type: Research article

    Medication-taking behavior, specifically non-adherence, is significantly associated with treatment outcome and is a major cause of relapse in the treatment of psychotic disorders. Non-adherence can be multifac...

    Authors: Menna Alene, Michael D Wiese, Mulugeta T Angamo, Beata V Bajorek, Elias A Yesuf and Nasir Tajure Wabe

    Citation: BMC Clinical Pharmacology 2012 12:10

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  4. Content type: Research article

    Paracetamol (acetaminophen) is generally considered a safe medication, but is associated with hepatotoxicity at doses above doses of 4.0g/day, and even below this daily dose in certain populations.

    Authors: Roderick Clark, Judith E Fisher, Ingrid S Sketris and Grace M Johnston

    Citation: BMC Clinical Pharmacology 2012 12:11

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  5. Content type: Research article

    An accurate medication list at hospital admission is essential for the evaluation and further treatment of patients. The objective of this study was to describe the frequency, type and predictors of errors in ...

    Authors: Lina M Hellström, Åsa Bondesson, Peter Höglund and Tommy Eriksson

    Citation: BMC Clinical Pharmacology 2012 12:9

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  6. Content type: Research article

    Consistent with its effect on gastric emptying, exenatide, an injectable treatment for type 2 diabetes, may slow the absorption rate of concomitantly administered oral drugs resulting in a decrease in maximum ...

    Authors: Prajakti A Kothare, Mary E Seger, Justin Northrup, Kenneth Mace, Malcolm I Mitchell and Helle Linnebjerg

    Citation: BMC Clinical Pharmacology 2012 12:8

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  7. Content type: Research article

    Data on adverse drug reactions (ADRs) related to antiretroviral (ARV) use in public health practice are few indicating the need for ART safety surveillance in clinical care.

    Authors: George I Eluwa, Titilope Badru and Kesiena J Akpoigbe

    Citation: BMC Clinical Pharmacology 2012 12:7

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    The Erratum to this article has been published in BMC Clinical Pharmacology 2012 12:14

  8. Content type: Research article

    Acute paracetamol poisoning is a rapidly increasing problem in Sri Lanka. The antidotes are expensive and yet no health economic evaluation has been done on the therapy for acute paracetamol poisoning in the d...

    Authors: S M D K Ganga Senarathna, Shalini Sri Ranganathan, Nick Buckley and Rohini Fernandopulle

    Citation: BMC Clinical Pharmacology 2012 12:6

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  9. Content type: Research article

    Addressing the problem of preventable drug related morbidity (PDRM) in primary care is a challenge for health care systems internationally. The increasing implementation of clinical information systems in the ...

    Authors: Tobias Dreischulte, Aileen M Grant, Colin McCowan, John J McAnaw and Bruce Guthrie

    Citation: BMC Clinical Pharmacology 2012 12:5

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  10. Content type: Study protocol

    Contrast-induced nephropathy is a common complication of contrast administration in patients with chronic kidney disease and diabetes. Its pathophysiology is not well understood; similarly the role of intraven...

    Authors: Euan A Sandilands, Sharon Cameron, Frances Paterson, Sam Donaldson, Lesley Briody, Jane Crowe, Julie Donnelly, Adrian Thompson, Neil R Johnston, Ivor Mackenzie, Neal Uren, Jane Goddard, David J Webb, Ian L Megson, Nicholas Bateman and Michael Eddleston

    Citation: BMC Clinical Pharmacology 2012 12:3

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  11. Content type: Technical advance

    Therapeutic drug monitoring of immunosuppressive drugs in organ-transplanted patients is crucial to prevent intoxication or transplant rejection due to inadequate dosage. The commonly used immunoassays have be...

    Authors: Armin Buchwald, Karl Winkler and Thomas Epting

    Citation: BMC Clinical Pharmacology 2012 12:2

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  12. Content type: Research article

    We aimed to explore relations between symptomatic remission and functionality evaluation in schizophrenia patients treated with paliperidone extended-release (ER), as seen in a normal day-to-day practice, usin...

    Authors: Min-Wei Huang, Tsung-Tsair Yang, Po-Ren Ten, Po-Wen Su, Bo-Jian Wu, Chin-Hong Chan, Tsuo-Hung Lan, I-Chao Liu, Wei-Cheh Chiu, Chun-Ying Li, Kuo-Sheng Cheng and Yu-Chi Yeh

    Citation: BMC Clinical Pharmacology 2012 12:1

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  13. Content type: Research article

    Clinical effects and outcomes of a single dose etomidate prior to intubation in the intensive care setting is controversial. The aim of this study is to evaluate the association of a single dose effect of etom...

    Authors: Antoine J Cherfan, Hani M Tamim, Abdulrahman AlJumah, Asgar H Rishu, Abdulmajeed Al-Abdulkareem, Bandar A Al Knawy, Ali Hajeer, Waleed Tamimi, Riette Brits and Yaseen M Arabi

    Citation: BMC Clinical Pharmacology 2011 11:22

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  14. Content type: Research article

    Drospirenone/ethinyl-estradiol is an oral contraceptive (OC) that possesses unique antimineralocorticoid activity. It is conjectured that drospirenone, taken alone or concomitantly with spironolactone, may be ...

    Authors: Steven T Bird, Salvatore R Pepe, Mahyar Etminan, Xinyue Liu, James M Brophy and Joseph AC Delaney

    Citation: BMC Clinical Pharmacology 2011 11:23

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  15. Content type: Research article

    This study aimed at describing the type and dosage of psychopharmaceuticals dispensed to patients with psychiatric disorders and to assess the percentage of patients treated with antipsychotics and antidepress...

    Authors: Stefano Bianchi, Erica Bianchini and Paola Scanavacca

    Citation: BMC Clinical Pharmacology 2011 11:21

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  16. Content type: Research article

    Mandatory generic substitution (GS) was introduced in Finland at the beginning of April 2003. However, individual patients or physicians may forbid the substitution. GS was a significant change for Finnish med...

    Authors: Reeta Heikkilä, Pekka Mäntyselkä and Riitta Ahonen

    Citation: BMC Clinical Pharmacology 2011 11:20

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  17. Content type: Research article

    The choices for self-medication in Hong Kong are much diversified, including western and Chinese medicines and food supplements. This study was to examine Hong Kong public knowledge, attitudes and behaviours r...

    Authors: Joyce H You, Fiona Y Wong, Frank W Chan, Eliza L Wong and Eng-kiong Yeoh

    Citation: BMC Clinical Pharmacology 2011 11:19

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  18. Content type: Research article

    Misuse of antimicrobials (AMs) and antimicrobial resistance (AMR) are global concerns. The present study evaluated knowledge, attitudes and practices about AMR and AM prescribing among medical doctors in two l...

    Authors: Coralith García, Liz P Llamocca, Krystel García, Aimee Jiménez, Frine Samalvides, Eduardo Gotuzzo and Jan Jacobs

    Citation: BMC Clinical Pharmacology 2011 11:18

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  19. Content type: Research article

    Panitumumab is a fully human antibody against the epidermal growth factor receptor that is indicated for the treatment of metastatic colorectal cancer (mCRC) after disease progression on standard chemotherapy....

    Authors: Dohan Weeraratne, Alin Chen, Jason J Pennucci, Chi-Yuan Wu, Kathy Zhang, Jacqueline Wright, Juan José Pérez-Ruixo, Bing-Bing Yang, Arunan Kaliyaperumal, Shalini Gupta, Steven J Swanson, Narendra Chirmule and Marta Starcevic

    Citation: BMC Clinical Pharmacology 2011 11:17

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  20. Content type: Research article

    According to the World Health Organization (WHO) the cost of adverse drug reactions (ADRs) in the general population is high and under-reporting by health professionals is a well-recognized problem. Another wa...

    Authors: Andreas Vilhelmsson, Tommy Svensson, Anna Meeuwisse and Anders Carlsten

    Citation: BMC Clinical Pharmacology 2011 11:16

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  21. Content type: Research article

    Spontaneous reporting of adverse drug reactions (ADRs) is an important method for pharmacovigilance, but under-reporting and poor quality of reports are major limitations. The aim of this study was to evaluate...

    Authors: Marie-Louise Johansson, Staffan Hägg and Susanna M Wallerstedt

    Citation: BMC Clinical Pharmacology 2011 11:14

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  22. Content type: Research article

    In many but not in all neuropsychological studies buprenorphine-treated opioid-dependent patients have shown fewer cognitive deficits than patients treated with methadone. In order to examine if hypothesized c...

    Authors: Pekka Rapeli, Carola Fabritius, Hely Kalska and Hannu Alho

    Citation: BMC Clinical Pharmacology 2011 11:13

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