Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part B - Behavioral results

Table 2 Results of PDD-BI evaluations by Parents N = 25 for the 7-round group, and N = 15 for the 1-round group.

		Initial	St. Dev	Final	St. Dev	% Change
Maladaptive Behaviors
Sensory/Perceptual Approach Behaviors	7 Rounds	22.8	14.7	17.8	13.9	-22%*
	1 Round	20.0	13.6	13.7	13.4	-31%**
Ritualisms/Resistance to Change	7 Rounds	13.9	10.5	10.0	7.8	-28%**
	1 Round	15.0	8.5	11.5	8.2	-23%**
Arousal Regulation Problems
	7 Rounds	17.9	9.0	13.9	8.5	-22%**
	1 Round	14.9	6.6	12.1	8.8	-19%
Specific Fears
	7 Rounds	21.7	16.0	14.6	12.1	-33%**
	1 Round	18.7	10.3	15.9	11.1	-15%
Aggressiveness
	7 Rounds	13.4	9.8	9.8	6.7	-27%*
	1 Round	11.4	8.1	8.4	7.2	-26%*
Social Pragmatic Problems
	7 Rounds	16.9	9.2	14.5	9.2	-14%
	1 Round	13.9	7.5	9.9	7.5	-29%**
Semantic/Pragmatic Problems
	7 Rounds	15.2	7.6	12.5	7.3	-18%
	1 Round	11.1	5.6	9.6	4.5	-13%
AWP/C Composite Sensory+Ritual+SocPrag+Semantic+ Arousal+Fears+Agg
	7 Rounds	105.	58.6	79.5	49.9	-24%***
	1 Round	93.8	29.5	71.6	38.8	-24%***
Adaptive Behaviors:
Social Approach Behaviors
	7 Rounds	63.8	20.6	70.8	23.6	11%**
	1 Round	68.2	25.4	72.6	20.2	6%
Express (Phonological & Semantic Pragmatic)
	7 Rounds	41.4	28.2	43.6	27.1	+5%
	1 Round	44.0	34.9	51.3	31.5	+17%*
Learning, Memory, and Receptive Language
	7 Rounds	22.7	8.1	25.4	8.7	12%*
	1 Round	23.2	10.1	26.5	8.9	14%**
REXSCA/C Composite SocialApp+Express+LMRL
	7 Rounds	127	52.7	139	54.5	9%**
	1 Round	135	65.5	150	53.6	11%*
Autism Composite (Sensory, Ritual & Social Problems - Social Approach Behaviors - Expressive Language)
	7 Rounds	-53.1	66.4	-73.3	67.9	38%**
	1 Round	-63.5	65.1	-88.8	58.3	40%**

* P < 0.05
** P < 0.01
*** P < 0.001
The statistical significance of the change is indicated, based on a paired ttest.