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Table 2 Results of PDD-BI evaluations by Parents N = 25 for the 7-round group, and N = 15 for the 1-round group.

From: Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part B - Behavioral results

   Initial St. Dev Final St. Dev % Change
Maladaptive Behaviors       
Sensory/Perceptual Approach Behaviors 7 Rounds 22.8 14.7 17.8 13.9 -22%*
  1 Round 20.0 13.6 13.7 13.4 -31%**
Ritualisms/Resistance to Change 7 Rounds 13.9 10.5 10.0 7.8 -28%**
  1 Round 15.0 8.5 11.5 8.2 -23%**
Arousal Regulation Problems       
  7 Rounds 17.9 9.0 13.9 8.5 -22%**
  1 Round 14.9 6.6 12.1 8.8 -19%
Specific Fears       
  7 Rounds 21.7 16.0 14.6 12.1 -33%**
  1 Round 18.7 10.3 15.9 11.1 -15%
Aggressiveness       
  7 Rounds 13.4 9.8 9.8 6.7 -27%*
  1 Round 11.4 8.1 8.4 7.2 -26%*
Social Pragmatic Problems       
  7 Rounds 16.9 9.2 14.5 9.2 -14%
  1 Round 13.9 7.5 9.9 7.5 -29%**
Semantic/Pragmatic Problems       
  7 Rounds 15.2 7.6 12.5 7.3 -18%
  1 Round 11.1 5.6 9.6 4.5 -13%
AWP/C Composite Sensory+Ritual+SocPrag+Semantic+ Arousal+Fears+Agg       
  7 Rounds 105. 58.6 79.5 49.9 -24%***
  1 Round 93.8 29.5 71.6 38.8 -24%***
Adaptive Behaviors:       
Social Approach Behaviors       
  7 Rounds 63.8 20.6 70.8 23.6 11%**
  1 Round 68.2 25.4 72.6 20.2 6%
Express (Phonological & Semantic Pragmatic)
  7 Rounds 41.4 28.2 43.6 27.1 +5%
  1 Round 44.0 34.9 51.3 31.5 +17%*
Learning, Memory, and Receptive Language       
  7 Rounds 22.7 8.1 25.4 8.7 12%*
  1 Round 23.2 10.1 26.5 8.9 14%**
REXSCA/C Composite SocialApp+Express+LMRL       
  7 Rounds 127 52.7 139 54.5 9%**
  1 Round 135 65.5 150 53.6 11%*
Autism Composite (Sensory, Ritual & Social Problems - Social Approach Behaviors - Expressive Language)      
  7 Rounds -53.1 66.4 -73.3 67.9 38%**
  1 Round -63.5 65.1 -88.8 58.3 40%**
  1. * P < 0.05
  2. ** P < 0.01
  3. *** P < 0.001
  4. The statistical significance of the change is indicated, based on a paired ttest.