Table 1 Peak Changes in Physiological Variables in Response to Inhaled l-Methamphetamine, IV phenylephrine and IV l-methamphetamine.

Systolic Blood Pressure (mmHg)

11.8 (16.2)^‡§||**

12.3 (20.5)^‡§||**

- 1.2 (16.0)

0.9 (10.1)

1.4 (9.8)

2.9 (9.3)

0.03

Diastolic Blood Pressure (mmHg)

8.7 (8.9)^||**

6.6 (9.9)^||

9.0 (12.4)^||**

1.9 (8.3)

-2 (10.2)

7.4 (12.5)^||

0.04

Heart Rate (beats/min)

1.3 (12.3)

4.2 (19.2)

2.3 (14.3)

2.8 (9.7)

-4.2 (7.9)

- 0.33 (8.4)

0.62

Respiratory Rate (breaths/min)

0.17 (4.3)

3 (2.5)*^§||**

2.4 (3.5)^§||

- 1.9 (4.8)

-1.5 (3.3)

0.42 (4.4)

0.003

Core Temperature (°C)

0.13 (0.8)

- 0.32 (0.9)

0.21 (0.9)

- 0.19(0.6)

0.08 (0.4)

0.09 (0.2)

0.41