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Table 2 Results of single dose trials in dental and postsurgical pain for comparison of dexketoprofen with placebo, and dexketoprofen with ketoprofen

From: Systematic review of dexketoprofen in acute and chronic pain

Dexketoprofen versus placebo
  Number of Percent of patients with at least 50% pain relief   
Dexketoprofen dose (mg) Trials Patients Dexketoprofen Placebo Relative benefit (95% CI) NNT (95% CI)
All trials
10/12.5 mg 5 462 45 17 3.4 (2.2 to 5.6) 3.5 (2.7 to 4.9)
20/25 mg 5 455 50 17 3.9 (2.4 to 6.3) 3.0 (2.4 to 3.9)
50 mg 1 67 56 8 6.7 (1.7 to 26) 2.1 (1.5 to 3.5)
Dental
10/12.5 mg 3 261 47 13 3.5 (2.2 to 5.6) 3.0 (2.3 to 4.4)
20/25 mg 3 254 52 13 3.9 (2.4 to 6.3) 2.6 (2.0 to 3.5)
50 mg 1 67 56 8 6.7 (1.7 to 26) 2.1 (1.5 to 3.5)
Postsurgical
10/12.5 mg 2 201 43 21 2.1 (1.4 to 3.3) 4.4 (2.8 to 9.7)
20/25 mg 2 201 47 21 2.3 (1.5 to 3.6) 3.7 (2.5 to 7.0)
Dexketoprofen versus ketoprofen
  Number of Percent of patients with at least 50% pain relief   
Dexketoprofen/ketoprofen dose (mg) Trials Patients Dexketoprofen Ketoprofen Relative benefit (95% CI) NNT (95% CI)
All trials       
12.5 vs 50 3 287 44 35 0.8 (0.5 to 1.2) not calculated
25 vs 50 3 284 51 35 1.1 (0.7 to 1.5) not calculated
50 vs 100 1 247 82 77 1.1 (0.9 to 1.2) not calculated
25/50 vs 50/100 4 531 65 54 1.2 (1.1 to 1.4) 8.8 (5.1 to 33)