Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005

Patel, Hitesh; Bell, Derek; Molokhia, Mariam; Srishanmuganathan, Janakan; Patel, Mitesh; Car, Josip; Majeed, Azeem

doi:10.1186/1472-6904-7-9

Table 3 Annual number of Hospital Episode Statistics finished consultant episodes with a primary diagnosis for an ADR (ICD-10 code)

From: Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005

ICD-10		1998–9	1999–00	2000–1	2001–2	2002–3	2003–4	2004–5	% Change 1998–2005
D59.0/2	Drug induced haemolytic anaemia	15	30	28	37	34	36	154	926.7
D61.1	Drug induced aplastic anaemia	101	116	114	186	182	162	241	138.6
E03.2	Hypothyroidism due to medicaments	23	23	12	12	19	13	26	13.0
E27.3	Drug induced adrenocortical failure	24	22	24	38	39	53	59	145.8
F11	Mental disorders due to opioids	4360	4287	4398	4187	3916	3690	3746	-14.1
F13	Mental disorders due to sedatives/hypnotics	223	247	247	239	232	206	189	-15.2
F19	Mental disorders due to multiple psychoactive drugs	3513	3137	2725	2643	2601	2690	2775	-21.0
G21.0	Malignant neuroleptic syndrome	101	106	121	108	102	93	128	26.7
G21.1	Drug induced Parkinsonism	145	115	124	133	112	108	149	2.8
G24.0	Drug induced dystonia	149	130	145	130	115	152	109	-26.8
G25.1/4/6	Drug induced extrapyramidal syndrome/chorea/tics	136	146	110	125	44	51	48	-64.7
G72.0	Drug induced myopathy	47	53	51	51	57	39	55	17.0
H91.0	Ototoxic hearing loss	2	5	3	3	2	U/C¹	U/C	U/C
I42.7	Drug induced cardiomyopathy	25	25	53	38	67	77	61	144.0
J70.2/3/4	Drug induced interstitial lung disorders	54	45	43	43	86	71	94	74.1
K71	Drug induced liver disease	406	318	372	351	459	437	448	10.3
L56.0/1	Drug induced phototoxicity	4	5	2	4	1	3	5	25.0
M10.2	Drug induced gout	30	27	13	24	22	22	34	13.3
M32.0	Drug induced systemic lupus erythematosus	17	20	12	13	14	10	26	52.9
M34.2	Drug induced systemic sclerosis	3	3	4	3	U/C	U/C	U/C	U/C
N14	Drug induced nephropathy	60	69	92	85	100	318	414	590.0
T88.3	Malignant hyperthermia due to anaesthesia	6	4	10	3	3	5	4	-33.3
T88.6	Drug induced anaphylaxis	366	435	399	384	375	469	563	53.8
T88.7	Unspecified adverse drug effect	696	737	721	602	664	748	1068	53.4
Total		10506	10105	9823	9442	9246	9453	10396	-1.0

¹U/C – unclassified: data not available due to a coding change

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