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Table 4 Adverse events occurring in ≥10% of subjects in any treatment group

From: Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone

Event, n(%)

8 mg (n= 31)

16 mg (n= 31)

32 mg (n= 31)

64 mg (n= 32)

Asthenia

2 (6)

5 (16)

3 (10)

5 (16)

Nausea

4 (13)

5 (16)

3 (10)

3 (9)

Headache

2 (6)

3 (10)

5 (16)

3 (9)

Chest pain

0 (0)

0 (0)

3 (10)

2 (6)