Figure 6
From: Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilat
Plasma ramipril (top panels) and ramiprilat (bottom panels) following IV ramipril for subject 4. Left column: early time data on absolute scale. Right column: long time data on semi-log scale. The open squares are the experimental plasma values. The dashed red line indicates ramipril detectable limit and the red square indicates that the plasma value was below this limit.