Figure 17From: Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilatPBPK model prediction of the true in vivo fraction of C (red) and N (black) site of plasma ACE that is inhibited by ramiprilat (black) following IV ramiprilat (top), IV ramipril (middle) and oral ramipril (bottom) for subject 4. The open squares are the experimental plasma ACE activity determined by the standard assay for subject 4.Back to article page