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Figure 4 | BMC Clinical Pharmacology

Figure 4

From: Physiologically based pharmacokinetic modeling of arterial – antecubital vein concentration difference

Figure 4

Comparison of thiopental PBPK model with the experimental data of Stanski et. al. [10] (left column) and Barratt et. al. [9] (right column). The top panels compare the model arterial (red) and antecubital vein (blue) concentration with the experimental data (squares). The bottom panels compare the model antecubital vein/arterial concentration ratio (black line) versus the experimental values (squares). Using a fractional contribution of muscle to antecubital vein blood of 0.05.

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BMC Clinical Pharmacology

ISSN: 1472-6904