Figure 1From: Comparison of renal effects of ibuprofen versus indomethacin during treatment of patent ductus arteriosus in contiguous historical cohorts Mean urine output and creatinine values for all patients by drug. Comparison of mean urine output and creatinine values for all patients during the first course of therapy, by treatment drug. Indomethacin group (solid line) and Ibuprofen group (dashed line). PRE - pre-treatment baseline; 1st - end of first course of treatment. * denotes statistically significant (p < 0.05) change from treatment baseline; § denotes statistically significant (p < 0.05) difference in change from baseline between treatment groups.Back to article page