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Table 2 Risk of UGIB and perforation associated with aspirin use

From: Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations

 

All cases

Controls

Adjusted RR*

 

(N=2,105)

(N=11,500)

(95%CI)

Non-use

1,696

10,157

1 (reference)

Current use (1-30)

287

837

2.0 (1.7-2.3)

   Use within 1-7

259

771

2.0 (1.7-2.3)

   days time window

   

   Use within 8-30

28

66

2.3 (1.4-3.7)

   days time window

   

Recent use (31-180)

37

123

1.5 (1.0-2.3)

   Use within 31-60

14

45

1.7 (0.9-3.3)

   days time window

   

   Use within 61-180

23

78

1.5 (0.9-2.5)

   days time window

   

Past use (>180)

85

383

1.1 (0.8-1.4)

  1. * Adjusted for sex, age, calendar year, antecedents of gastrointestinal disorders, smoking status, alcohol consumption and use of NSAIDs, anticoagulants, steroids, SSRIs and paracetamol.