Table 4 Pharmacokinetic Geometric Mean ratios of AVI-014/Filgrastim at 8 μg/kg
PK parameter | Dose μg/kg | Geometric Mean AVI-014 (n = 8) | Geometric Mean Filgrastin (n = 8) | P value | Geometric Mean Ratio (90% CI) |
|---|---|---|---|---|---|
AUC(0–72) | 8 | 301,979 | 340,837 | 0.3669 | 0.89 (0.69, 1.14) |
Cmax | 8 | 30,467 | 40,325 | 0.0550 | 0.76 (0.58, 0.98) |