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Table 3 Comparison of change in average urine excretion compared to baseline for participants who completed six rounds of phase 2 (n = 20).

From: Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A - Medical results

Element Baseline (mcg/g- creatinine) Change after 1stdose Change after 9thdose Change after round 2 Change after round 4 Change after round 6
Pb 0.64 935%*** 1562%*** 1001%*** 1063%*** 1005%***
Sn 3.5 118%* 269% 205% 213% 115%
Bi 0.06 312% 296% 787% 261% 11%
U 0.014 29% 79% -32% -11% 282%+
Hg 0.85 120%* 37% 98%*** 70% 59%+
Tl 0.16 54%** 44%* 13% 18% 28%
Sb 0.10 67%+ 26% 9% 23% 27%
W 0.41 36%+ -11% 14% 52% 25%
Al 8.3 125% 1% 26% 38% -12%
Ni 5.8 -2% 25% 36%+ 68%* 25%
Cd 0.35 14% -32%* -7% 0% -17%
As 31 4% -13% -39%*** -42%*** -31%+
  1. + P < 0.1
  2. *P < 0.05
  3. ** P < 0.01
  4. *** P < 0.001
  5. Significant results are highlighted in bold font.