BMC Clinical Pharmacology

Table 4 Factors associated with hyperglycemia with above borderline and adverse readings*

From: Antihypertensive drug class and impaired fasting glucose: a risk association study among Chinese patients with uncomplicated hypertension

	Above Borderline readings		Adverse readings
	Odds Ratios (95% CI)	p	Odds Ratios (95% CI)	p
Age (years)
<50	1.0 (ref)		1.0 (ref)
50–59	1.249 (0.648, 2.408)	0.506	1.776 (0.533, 5.919)	0.349
60–69	1.344 (0.654, 2.759)	0.421	0.784 (0.167, 3.685)	0.758
≥ 70	2.103 (1.051, 4.207)	0.036	1.359 (0.372, 4.962)	0.643
Gender
Male	1.0 (ref)		1.0 (ref)
Female	1.464 (0.927, 2.313)	0.102	0.223 (0.074, 0.674)	0.008
Payment status
Fee waiver	1.0 (ref)		1.0 (ref)
Fee payers	1.328 (0.789, 2.236)	0.286	0.759 (0.320, 1.798)	0.530
District of residence
Shatin	1.0 (ref)		1.0 (ref)
Taipo	0.967 (0.433, 2.156)	0.934	1.676 (0.588, 4.778)	0.334
North	0.707 (0.392, 1.273)	0.248	0.311 (0.115, 0.841)	0.021
Others	0.909 (0.363, 2.279)	0.839	N/A	N/A
Clinics
GOPC	1.0 (ref)
FMSC	0.652 (0.234, 1.818)	0.414	0.299 (0.036, 2.507)	0.266
Staff clinics	2.071 (0.717, 5.984)	0.179	0.614 (0.066, 5.732)	0.668
Drug class
RAS	1.0 (ref)		1.0 (ref)
β-blockers	1.360 (0.497, 3.721)	0.549	0.518 (0.125, 2.151)	0.365
Thiazide	1.252 (0.443, 3.537)	0.672	0.466 (0.099, 2.190)	0.334
CCB	0.888 (0.320, 2.463)	0.819	0.575 (0.140, 2.353)	0.441

(C.I: confidence intervals, GOPC: General Out-patient clinics, FMSC: Family Medicine Specialist Clinics. RAS: drugs acting on the renin angiotensin system; CCB: Calcium channel blockers.
*Above borderline readings were defined as fasting glucose ≥ 6.1 mmol/l; adverse readings as fasting glucose ≥ 7.0 mmol/l. All adjusted Odds Ratio were adjusted for age, gender, payment status, district of residence, service types of attended clinics and other drug classes as listed in table
N/A: No patients presented with adverse readings)

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