Table 1 Ethic committee approvals
| Study | Ethical Committee |
|---|---|
|
- single-dose, comparing 1 and 2 mg lozenges with 2 mg gum - multiple-dose, comparing 1 mg lozenge with 2 mg gum | CCPPRB de Franche-Comté, France |
| - multiple-dose, comparing 1 and 2 mg lozenges with 4 mg gum | CCPPRB of the Hôtel-Dieu Hospital (Lyon – France) |
| - safety assessment of 1 mg lozenge after swallowing | CREC Regipharm (Brussels – Belgium) |
| - French efficacy trial | CCPPRB of the Pitié-Salpêtrière Hospital (Paris – France) |
| - US efficacy trial | IRB at Research Testing Laboratories, Inc. (Great Neck, NY, USA) |