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Table 1 Model human adipose blood flow heterogeneity.

From: Heterogeneity of human adipose blood flow

Solute Ref Ave F l/kg/min F1 l/kg/min V1 fract F2 l/kg/min V2 fract F3 l/kg/min V2 fract Time Method
Volatile Anesthetics This ms. 0.044 0.0739 0.5 0.0141 0.5    6 days PBPK N = 2
   0.044 0.095 0.33 0.031 0.33 0.0059 0.33 6 days PBPK N = 3
  [38] 0.071 0.213 .26 0.022 0.74    5 days PBPK N = 2
   0.05 0.097 .41 0.019 0.59     
  [4, 5] 0.06–0.071 .11–.15 ≈ 0.5 0.021–0.024 ≈ 0.5    6 days Compartmental
Propofol [14] 0.042 0.042 1.0      600 min PBPK N = 1
Toluene [55] 0.032 0.032 1.0      4 days PBPK N = 1
Toluene [53] 0.024 0.042 0.4 0.013 0.5 0.0 0.1 20 hr PBPK N = 2
Styrene [54] 0.028 0.052 0.4 0.014 0.5 0.0 0.1 20 hr PBPK N = 2
  1. (Vi = fraction of total adipose volume in compartment i; Fi = perfusion rate in compartment i). (Note: in toluene [53] and styrene [54] PBPK model it is assumed that 10% of the adipose tissue has zero blood flow).