Table 2 Intra- and inter-assay accuracy and precision (CV%) for paclitaxel and docetaxel determinations in plasma.
Concentration [nM] | Intra-assay variability | Inter-assay variability | |||||
|---|---|---|---|---|---|---|---|
n | Accuracy (%) | CV (%) | n | Accuracy (%) | CV (%) | ||
Paclitaxel | 1000 | 3 | 89 | 2 | 5 | 100 | 2 |
100 | 3 | 103 | 6 | 5 | 103 | 3 | |
10 | 3 | 111 | 2 | 5 | 104 | 9 | |
1.2 | 3 | 104 | 8 | 5 | 108 | 14 | |
0.7 | 3 | 105 | 20 | ND | |||
Docetaxel | 750 | 3 | 100 | 1 | 5 | 101 | 3 |
50 | 3 | 97 | 1 | 5 | 94 | 6 | |
5 | 3 | 99 | 4 | 5 | 100 | 5 | |
2 | 5 | 93 | 4 | ND | |||
1 | 5 | 96 | 12 | ND | |||