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Table 5 Biological coefficients of variation (CV) of morphine, morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G) serum concentrations during four consecutive days of oral or subcutaneous morphine treatment. All values are given as median and range.

From: Day-to-day variations during clinical drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study

  Biological coefficient of variation %
  Oral morphine Subcutaneous morphine
Morphine 46 (13–103) 10 (0–36)
M6G 25 (1–72) 13 (2–40)
M3G 18 (0–57) 9 (0–34)