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Figure 10 | BMC Clinical Pharmacology

Figure 10

From: Physiologically based pharmacokinetic modeling of arterial – antecubital vein concentration difference

Figure 10

Comparison of methylene chloride PBPK model arterial (red line) and antecubital vein (blue line) concentrations with the experimental data (squares) of Astrand et. al. [16] (top panel). The bottom panel compares the model antecubital vein/arterial concentration ratio (black line) versus the experimental values (squares). Using a fractional contribution of muscle to antecubital vein blood of 0.5.

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