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Table 5 Interstitial albumin volume as fraction of interstitial EDTA volume (VI A/VI E); the interstitial albumin concentration relative to plasma albumin (CI/CP); and the product KA = (VI A/VI E)(CI/CP).

From: The pharmacokinetics of the interstitial space in humans

Species

Reference

Organ

CI/CP

VI A/VI E

KA

Comments

Rat

[64]

sk. mus.

0.8

0.73

0.58

Constant infusion of I125 rat serum albumin. Wick tissue albumin

  

skin

0.69

0.6

0.4

 
  

tendon

0.61

0.45

0.27

 
 

[50]

skin-dermis

0.72

0.44

0.32

 
  

skin-subcut

0.72

0.57

0.41

 

Rabbit

[79]

sk. mus.

0.76

0.53

0.4

Lymph albumin

  

skin.

0.49

0.47

0.23

Â