Figure 9
From: The pharmacokinetics of the interstitial space in humans
Comparison of PBPK linear (left) or semi-log (right) plots of model predictions and experimental data for cefatrizine from Pfeffer et. al. [31]. The top row is for the flow limited model (fclear = 1) with an average error between PBPK model and experimental data of 5.4%. The addition of a small capillary permeability limitation does not significantly improve the fit (not shown).