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Table 2 Pharmacokinetic Values

From: Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects

PARAMETER THIAMINE DOSE
  100 mg 500 mg 1500 mg
AUC0-10 hr (nmol/Liter × hours)    
   whole blood 214 ± 69 623 ± 178 2046 ± 1222
   plasma 177 ± 62 612 ± 257 2059 ± 1415
Cmax (nmol/Liter)    
   whole blood 40 ± 11 95 ± 27 385 ± 188
   plasma 39 ± 13 113 ± 42 397 ± 250
Tmax (hours)    
   whole blood 3.43 ± 1.69 4.14 ± 1.57 4.14 ± 0.90
   plasma 3.14 ± 1.05 3.18 ± 0.98 4.27 ± 1.01
  1. All values are presented as mean ± standard deviation. p < 0.05 for all pairwise comparisons (plasma and whole blood values were analyzed separately)