BMC Clinical Pharmacology

Table 3 Treatment Efficacy by Number of Treatment Courses

From: Comparison of renal effects of ibuprofen versus indomethacin during treatment of patent ductus arteriosus in contiguous historical cohorts

	Indomethacin			Ibuprofen
Number of Courses Used	1	2	3	1	2	3
Total N	101	41	19	118	28	37
PDA Closed, n (%)	89 (88.1)	18 (43.9)	3 (15.8)	108 (92.3)	15 (53.6)	7 (18.9)
PDA Ligations	8 (7.9)	22 (53.7)*	15 (78.9)	3 (2.6)	8 (28.6)*	26 (70.3)

PDA, patent ductus arteriosus.
Not all patients whose PDA remained open needed to have a surgical ligation.
* denotes statistically significant difference between treatments, p < 0.05.

Back to article page