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Figure 2 | BMC Clinical Pharmacology

Figure 2

From: Comparison of renal effects of ibuprofen versus indomethacin during treatment of patent ductus arteriosus in contiguous historical cohorts

Figure 2

Mean urine output and creatinine values by drug and number of courses. Comparison of mean urine output and creatinine values by treatment drug for subgroups and defined by the total number of courses received. Left panel: patients who received only one course of either ibuprofen or indomethacin. Middle panel: patients who received total of two courses. Right panel: patients who received 3 total courses of medical treatment. Indomethacin group (solid line) and Ibuprofen group (dashed line). PRE - pre-treatment baseline; 1st - end of first course of treatment, POST - 3-5 days after the last course of treatment. * denotes statistically significant (p < 0.05) change from baseline within a treatment group. § denotes statistically significant (p < 0.05) difference in change from baseline between treatment groups.

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BMC Clinical Pharmacology

ISSN: 1472-6904