Table 6 AEs reported in >1 subject with normal renal function and varying degrees of renal impairment
| Â | Â | Degree of renal impairment | ||
|---|---|---|---|---|
Adverse event, n (%) | Normal renal function (n = 18) | Mild (n = 12) | Moderate (n = 9) | Severe (n = 9) |
Any AE | 14 (78) | 7 (58) | 8 (89) | 7 (78) |
Headache | 14 (78) | 6 (50) | 5 (56) | 4 (44) |
Nasopharyngitis | 1 (6) | 1 (8) | 2 (22) | 0 |
Fatigue | 0 | 1 (8) | 1 (11) | 2 (22) |
Somnolence | 2 (11) | 1 (8) | 0 | 0 |
Nausea | 1 (6) | 1 (8) | 0 | 1 (11) |
Neck pain | 0 | 2 (17) | 0 | 0 |
Back pain | 1 (6) | 1 (8) | 0 | 0 |
Dizziness | 0 | 0 | 2 (22) | 0 |
Dyspepsia | 1 (6) | 0 | 0 | 1 (11) |