|  | Degree of hepatic impairment |  | Degree of renal impairment | ||||
---|---|---|---|---|---|---|---|---|
 | Normal hepatic function (n = 8) | Mild (n = 8) | Moderate (n = 8) | Severe (n = 8) | Normal renal function (n = 18) | Mild (n = 12) | Moderate (n = 9) | Severe (n = 9) |
Male, n (%) | 5 (63) | 6 (75) | 5 (63) | 5 (63) | 13 (72) | 9 (75) | 7 (78) | 7 (78) |
Female, n (%) | 3 (38) | 2 (25) | 3 (38) | 3 (38) | 5 (28) | 3 (25) | 2 (22) | 2 (22) |
Mean age, years (range) | 58.4 (55-62) | 56 (45-63) | 59.3 (49-68) | 52 (37-67) | 60 (47-71) | 58 (38-71) | 60 (48-69) | 57 (32-69) |