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Table 2 Demographic and baseline characteristics for subjects in the hepatic and renal impairment studies

From: Pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with hepatic or renal impairment: two open-label comparative studies

   Degree of hepatic impairment   Degree of renal impairment
  Normal hepatic function (n = 8) Mild (n = 8) Moderate (n = 8) Severe (n = 8) Normal renal function (n = 18) Mild (n = 12) Moderate (n = 9) Severe (n = 9)
Male, n (%) 5 (63) 6 (75) 5 (63) 5 (63) 13 (72) 9 (75) 7 (78) 7 (78)
Female, n (%) 3 (38) 2 (25) 3 (38) 3 (38) 5 (28) 3 (25) 2 (22) 2 (22)
Mean age, years (range) 58.4 (55-62) 56 (45-63) 59.3 (49-68) 52 (37-67) 60 (47-71) 58 (38-71) 60 (48-69) 57 (32-69)