Skip to main content

Table 2 Demographic and baseline characteristics for subjects in the hepatic and renal impairment studies

From: Pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with hepatic or renal impairment: two open-label comparative studies

  

Degree of hepatic impairment

 

Degree of renal impairment

 

Normal hepatic function (n = 8)

Mild (n = 8)

Moderate (n = 8)

Severe (n = 8)

Normal renal function (n = 18)

Mild (n = 12)

Moderate (n = 9)

Severe (n = 9)

Male, n (%)

5 (63)

6 (75)

5 (63)

5 (63)

13 (72)

9 (75)

7 (78)

7 (78)

Female, n (%)

3 (38)

2 (25)

3 (38)

3 (38)

5 (28)

3 (25)

2 (22)

2 (22)

Mean age, years (range)

58.4 (55-62)

56 (45-63)

59.3 (49-68)

52 (37-67)

60 (47-71)

58 (38-71)

60 (48-69)

57 (32-69)