Figure 2From: Pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with hepatic or renal impairment: two open-label comparative studies Forest plot of the ratios of zibotentan exposure. Forest plot of the ratios of zibotentan exposure (AUC) in subjects with varying degrees of renal impairment compared with subjects with normal renal function, and in subjects with varying degrees of hepatic impairment compared with subjects with normal hepatic function.Back to article page