Table 1 Characteristics of women included in the study cohort by type of progestin oral contraceptive used (n = 1,148,183)

Number of patients

139,871

224,408

17,295

180,720

93,818

234,105

228,276

29,690

Age

28.7

29.0

28.8

29.0

30.5

29.7

26.9

29.7

Mean follow up (days)

327

272

327

304

240

230

307

249

Number of cases

267

488

33

349

200

433

499

56

Covariates (%)

   CKD †

0.15

0.09

0.08

0.09

0.12

0.15

0.08

0.19

   Diabetes

4.10

4.10

4.41

3.93

4.13

4.12

3.37

5.43

   Hypertension

8.34

8.47

8.53

8.62

9.78

8.89

6.55

10.82

   IBD*

0.94

1.03

1.22

1.00

1.03

0.85

0.75

0.98

   Obesity

11.59

12.53

12.44

11.22

10.75

10.08

9.50

13.60

PCOS □

4.47

5.78

5.00

2.11

2.80

2.81

2.21

3.48

   PTS (PMS/PMDD) ‡

3.63

5.53

3.04

3.01

3.26

1.95

1.69

2.73

   Smoking

6.62

5.94

8.48

7.36

6.43

6.49

6.97

9.00

   ACEI/ARB §

0.50

0.47

0.56

0.60

0.75

0.67

0.42

0.80

   NSAIDS ʗ

5.67

4.84

5.79

5.56

5.13

5.90

4.77

6.09

   Spironolactone

0.43

0.74

0.84

0.28

0.32

0.19

0.32

0.29

   Other Medications ʒ

0.46

0.36

0.56

0.46

0.37

0.35

0.27

0.44