Constipation and diarrhoea - common adverse drug reactions? A cross sectional study in the general population

Table 3 Independent predictors for constipation and diarrhoea

	Independent predictor	OR
		Estimates	95% CI	p-value
Constipation	Use of drug	1.30	1.06 to 1.59	0.012
	Gender (women)	3.24	2.61 to 4.02	<0.001
	Age (years)	1.01	1.003 to 1.02	0.005
	BMI (body mass index)	0.95	0.93 to 0.97	<0.001
	Frequency of use of alcohol	0.94	0.89 to 0.99	0.024
	Musculoskeletal complaints	1.04	1.002 to 1.09	0.042
	Angina pectoris	1.86	1.21 to 2.85	0.004
	Multiple sclerosis	2.41	1.03 to 5.66	0.043
Diarrhoea	Use of drugs	1.37	1.08 to 1.74	0.011
	Gender (Women)	0.69	0.55 to 0.86	0.001
	Age (years)	0.999	0.99 to 1.01	0.824 (ns)
	Frequency of use of alcohol	1.10	1.03 to 1.17	0.006
	Years of education/schooling	0.96	0.93 to 0.995	0.023
	HSCL 10 (Mood disorders)	1.70	1.37 to 2.11	<0.001
	Osteoporosis	2.20	1.21 to 3.97	0.009

Multivariable logistic regression analyses with stepwise selection of variables. Use of drugs and not the individual drugs were included in the models. Age and gender were included in the models independent of significance.