Age (years) | Sex | Suspected substance/s | Dose | ADR diagnosis | Serious* | Unexpected* | New drug and not common ADR** | Treatment duration | Time to ADR onset | Positive dechallange | Concomitant medication | Causality assessment* |
---|---|---|---|---|---|---|---|---|---|---|---|---|
55 | F | Acetylsalicylic acid/caffeine | 500/50 mg | Pruritus | N | Y | N | 1 dose | Hours | NR | NR | Probable |
63 | F | Acetylsalicylic acid | NR | Haemorrhagic gastric ulcer | Y | N | N | NR | NR | Y | Candesartan | Possible |
80 | F | Acetylsalicylic acid | NR | Gastrointestinal haemorrhage | Y | N | N | 8 weeks | 8 weeks | Died | NR | Possible |
56 | F | Citalopram | 60 mg | Nail disorder | N | Y | N | NR | NR | Medication continued | Folic acid Propiomazine Diazepam Levothyroxine | Possible |
78 | F | Citalopram Enalapril Dextropropoxyphene Omeprazole Bendroflumethiazide | 20 mg 15 mg 150 mg 20 mg 5 mg | Hyponatraemia Confusion | Y | N | N | NR | NR | Medication continued | Dipyridamole Budesonide/ formoterol Tiotropium Cholecalciferol/calcium Macrogol, combinations Vitamin B-complex Paracetamol Cyanocobalamin Sodium picosulfate Ferrous sulphate Levothyroxine Antacids, salt combination Acetylcysteine | Possible |
38 | F | Enalapril | 5 mg | Yawning | N | Y | N | 3 weeks | Days | Y | N | Possible |
69 | F | Enalapril | 20 mg | Diplopia | N | Y | N | NR | NR | Medication continued | N | Possible |
35 | F | Levonorgestrel | NR | Fatigue Myalgia | N | Y Y | N | 15 months | Days | Y | Paracetamol Tramadol | Possible |
38 | F | Levonorgestrel | NR | Ectopic pregnancy | Y | N | N | 4 years | 4 years | Y | N | Possible |
49 | M | Varenicline | 1 mg | Thrombophlebitis | N | Y | Y | 2 months | 2 months | NR | Atenolol | Possible |
61 | F | Varenicline | 2 mg | Confusion | N | Y | Y | 2 weeks | NR | Y | Dipyridamole Simvastatin | Possible |
62 | F | Varenicline | NR | Macula-degeneration | N | Y | Y | 4 months | 5 months | NR | NR | Unclassifiable |
66 | F | Varenicline | NR | Oedema legs | Y | Y | Y | 5 weeks | 4 weeks | N | Naproxen Omeprazole Folic acid | Possible |