Table 1 Baseline characteristics of patients on statin therapy and non-statin therapy
From: Association between statin therapy and outcomes in critically ill patients: a nested cohort study
| Â | Statin (n = 107) | Non-Statin (n = 656) | P-value |
|---|---|---|---|
Age, mean ± SD (yrs) | 68.8 ± 11.0 | 49.3 ± 21.7 | < 0.0001 |
Female gender, no. (%) | 44 (41.1) | 164 (25) | 0.0005 |
APACHE II, mean ± SD | 27.2 ± 6.9 | 23.0 ± 8.1 | < 0.0001 |
SOFA day 1, mean ± SD | 9.3 ± 3.2 | 9.2 ± 3.5 | 0.92 |
Creatinine, mean ± SD, μmol/L* | 200.8 ± 152.6 | 152.3 ± 152.1 | 0.002 |
Platelets, mean ± SD, x109/L | 270.7 ± 117.8 | 193.3 ± 123.3 | 0.0001 |
Bilirubin, mean ± SD, μmol/l | 26.4 ± 63.6 | 31.6 ± 55.2 | 0.50 |
INR, mean ± SD | 1.5 ± 0.7 | 1.5 ± 0.9 | 0.72 |
GCS, mean ± SD | 9.4 ± 4.5 | 8.5 ± 4.0 | 0.05 |
ICU admission category, no. (%) | Â | Â | Â |
Postoperative | 4 (3.7) | 119 (18.1) | 0.0002 |
Nonoperative | 103 (96.3) | 537 (81.9) | Â |
History of diabetes, no. (%) | 84 (78.5) | 219 (33.4) | < 0.0001 |
Mechanically ventilated, no. (%) | 92 (86.0) | 591 (90.1) | 0.20 |
Vasopressors, no. (%) | 73 (68.2) | 423 (64.5) | 0.45 |
Sepsis, no. (%) | 28 (26.2) | 166 (25.3) | 0.85 |
Severe sepsis, no. (%) | 26 (24.3) | 207 (31.5) | 0.13 |
Chronic respiratory, no. (%) | 33 (30.8) | 124 (18.9) | 0.005 |
Chronic cardiac, no. (%) | 54 (50.5) | 103 (15.7) | < 0.0001 |
Chronic renal, no. (%) | 29 (27.1) | 74 (11.3) | < 0.0001 |
Chronic liver, no. (%) | 4 (3.7) | 50 (7.6) | 0.15 |
Chronic immunocompromised, no. (%) | 10 (9.4) | 56 (8.5) | 0.78 |