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Table 3 Ciprofloxacin and Creatinine Clearance by continuous veno-venous haemodiafiltration.

From: An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration

Patient

ClCVVHDF

(L/hr)

ClCREAT

(L/hr)

FCVVHDF

Measured effluent

fluid rate

(L/hr)

Total Body

Clearance

(L/hr)

1 A

2.8

2.9

0.25

4.0

11.3

2 C

2.4

2.6

0.31

3.4

7.72

3 B

2.7

2.9

0.27

3.9

9.96

4 A

2.3

2.3

0.74

2.9

3.10

5 A

2.2

2.6

0.22

3.0

9.90

6 C

2.1

2.4

0.26

2.9

8.06

7 B

2.8

2.9

0.28

4.0

10.1

Mean +/- SD

2.47 +/- 0.29

2.66 +/- 0.25

0.26 ± 0.03*

3.35 +/- 0.50

8.60 ± 2.7

  1. * Excluding value from patient 4A