BMC Clinical Pharmacology

Table 3 Pharmacokinetic parameters for free phenoxodiol infused at a dose of 2 mg/kg/h.

From: Pharmacokinetics of phenoxodiol, a novel isoflavone, following intravenous administration to patients with advanced cancer

	Css (μg/ml)	Time to ss(h)	Acc T1/2 (h)	Cl (L/h)
1	0.92	0.67	0.13	1.08
2	0.65	1.00	0.20	1.53
4	0.77	1.00	0.20	1.28
5	0.66	1.00	0.20	1.51
6	0.96	0.67	0.13	1.03
Mean ± SD	0.79 ± 0.14	0.87 ± 0.18	0.17 ± 0.04	1.29 ± 0.23

Css is the plasma concentration at steady state. Time to steady state is the time taken to reach Css. Acc T1/2 is the accumulation half-life. Cl is the plasma clearance rate.

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