BMC Clinical Pharmacology

Table 2 Modifier

From: EVITA: a tool for the early EValuation of pharmaceutical Innovations with regard to Therapeutic Advantage

NNT	ARR	Modifier
prevention
<20	5-100%	2.0
20 - <50	<5%	1.75
50 - <100	<2%	1.5
100 - <175	<1%	1.25
175 - <300	<0.57%	1.0
300 - <500	<0.33%	0.75
500 - <1000	<0.2%	0.5
≥1000	<0.1%	0.25
treatment
NNT	ARR	Modifier
<3	>30%	2.0
3 - <10	10-30%	1.5
≥10	<10%	1.0

Assessment of the modifier for the efficiency score according to strength of effect given in "number needed to treat" (NNT) or "absolute risk reduction" (ARR).

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