| |
Adjusted*RR (95% CI)
|
---|
| |
All cases
|
UGIB
|
Perforation
|
---|
All sites
|
Plain
|
1.9 (1.6-2.3)
|
2.0 (1.6-2.4)
|
1.6 (1.1-2.5)
|
|
Coated
|
2.3 (1.6-3.2)
|
2.2 (1.5-3.2)
|
2.4 (1.1-5.0)
|
Gastric
|
Plain
|
2.0 (1.5-2.5)
|
2.0 (1.6-2.6)
|
- $
|
|
Coated
|
2.2 (1.4-3.6)
|
2.3 (1.4-3.8)
| |
Duodenal
|
Plain
|
1.6 (1.3-2.1)
|
1.5 (1.2-2.0)
|
1.8 (1.1-2.8)
|
|
Coated
|
2.2 (1.4-3.4)
|
1.9 (1.1-3.2)
|
2.9# (1.4-6.1)
|
-
* Adjusted for sex, age, calendar year, antecedents of gastrointestinal disorders, smoking status, alcohol consumption and use of NSAIDs, anticoagulants, steroids, SSRIs and paracetamol $ Only 3 cases of gastric perforation exposed to plain aspirin and none to coated aspirin # Based on 9 exposed cases and 142 controls