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Table 2 Cmax, AUC0-t, AUC0-inf and Tmax data

From: Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers

 

Sodium ibuprofen

(n = 22)

Ibuprofen/poloxamer

(n = 22)

Standard ibuprofen

(n = 22)

C max (μg/mL)

   

   Arithmetic mean

43.01

36.06

32.84

   Geometric LS mean

41.47

35.22

31.88

AUC 0-t (μg/mL/h)

   

   Arithmetic mean

120.57

124.10

119.10

   Geometric LS mean

117.79

120.55

115.28

AUC 0-inf (μg/mL/h)

   

   Arithmetic mean

122.88

126.72

121.99

   Geometric LS mean

119.73

122.75

117.71

T max (min)

   

   Median

35

75

90

  1. LS: least-squares