Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers

Table 1 Pharmacokinetic variables and their definitions

T_max	The time to the first occurrence of the maximum plasma concentration
C _max	The observed maximum plasma concentration
AUC _0-t	AUC to the last measurable plasma concentration (Cp), calculated by the linear trapezoidal rule
AUC _0-inf	AUC calculated by linear trapezoidal rule to the last measurable Cp with additional area calculated from Cp/Kel. Kel is the elimination rate constant calculated from the slope of the terminal portion of the plasma profile calculated by least-squares regression of log (concentration) against time