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Table 6 Quantitative drug use and potential drug-drug interactions at hospital admission and discharge

From: Evaluation of risk factor management of patients treated on an internal nephrology ward: a pilot study

 

Admission

Discharge

 

Total study population n = 102

Mean ± SDa

Range

Mean ± SDa

Range

P-valueb

Number of drugs per patient

10.9 ± 4.2

0-20

12.1 ± 4.3

2-21

<0.0001*

Number of pDDIsc per patient

1.9 ± 1.9

0-8

2.7 ± 2.5

0-11

<0.0001*

Number of pDDIsc per drug prescribed

0.2 ± 0.2

0-0.83

0.2 ± 0.2

0-0.64

0.0016*

TXd subgroup n = 49

     

Number of drugs per patient

12.6 ± 3.1

4-20

13.3 ± 3.2

5-20

0.055

Number of pDDIsc per patient

1.8 ± 2.4

0-8

2.7 ± 2.8

0-11

0.014*

Number of pDDIsc per drug prescribed

0.1 ± 0.1

0-0.53

0.2 ± 0.2

0-0,64

0.014*

  1. Only pDDIs classified as moderate or severe were included in the analysis.
  2. a SD = standard deviation
  3. b p = statistical significance according to the t-test
  4. c pDDIs = potential drug-drug interactions
  5. d TX = transplantation
  6. * Statistically significant