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Table 3 Precision of the vancomycin bioassay

From: Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics

Vancomycin concentration (mg/L)

Inhibition zone diameters (mean in mm ± SD)

Coefficient of variation (%) Intra-day

Coefficient of variation (%) Inter-day

128

18.00 ± 0.04

8.3

10.3

64

16.33 ± 0.02

5.6

10.5

32

14.16 ± 0.11

11.0

1.0

16

11.62 ± 0.37

7.4*

2.3

8

9.59 ± 0.00

4.6

6.5

  1. *An outlier value was excluded from the calculations (we only used five data to compute the CV)
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BMC Clinical Pharmacology

ISSN: 1472-6904