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Table 1 Patient characteristics

From: Expression of thymidine phosphorylase in peripheral blood cells of breast cancer patients is not increased by paclitaxel

Characteristics

Patients

Entered

8

Karnofsky performance score

90–100%

Age (years)

 

   Median (range)

65.5 years (range 53 – 73 y)

Stage (primary diagnosis)

 

   I

-

   II

6 (75%)

   III

-

   IV

1 (12.5%)

   Not available

1 (12.5%)

Ductal/Lobular

7/0

   Not available

1 (12.5%)

Grading

 

   1

-

   2

2 (25%)

   3

5 (62.5%)

   Not available

1 (12.5%)

Estrogens receptor/progesteron receptor positive

7/6

Her2 Status positive/negative (IHC/FISH*)

0/8

Adjuvant chemotherapy

3 (37.5%)

Adjuvant endocrine therapy

3 (37.5%)

Palliative endocrine therapy

4 (50%)

Prior anthracycline exposure

5 (62.5%)

Prior capecitabine exposure

2 (25%)

Time to recurrence

 

   Median (range)

87 months (13 – 148 m)

Treatment line

 

   First line

4 (50%)

   Second line

2 (25%)

   >/= Third line

2 (25%)

Metastatic sites

 

   Median (range)

2 (range 1 – 4)

   bones/soft tissue only

3 (37.5%)

   visceral only

-

   both

5 (62.5%)

Localisation

 

   Lung

1

   Liver

3

   Bones

5

   Lymph nodes

6

   Soft tissue

2

   Brain

1

   Skin

1

More than one metastatic site

7 (87.5%)

  1. * IHC: immunohistochemistry, Herceptest® (Dako A/S, Glostrup, Denmark); FISH: dual colour fluorescent in situ hybridization (PathVision® HER2 DNA probe kit, Vysis, Downers Grove, IL, USA)