From: Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone
Event, n(%)
8 mg (n= 31)
16 mg (n= 31)
32 mg (n= 31)
64 mg (n= 32)
Asthenia
2 (6)
5 (16)
3 (10)
Nausea
4 (13)
3 (9)
Headache
Chest pain
0 (0)