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Figure 1 | BMC Clinical Pharmacology

Figure 1

From: Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell®)

Figure 1

Nicotine plasma concentration after repeated intake (24 subjects). Nicotine plasma concentrations were determined in this multiple-dose bioequivalence trial with 24 volunteers from blood samples drawn before administration of each single dose (unconnected data points). Consecutive blood samples (connected data points) were drawn after administration of dose 1 (t = 0) and dose 12 (t = 11 h). The insert shows a blood nicotine peak after dosing at steady state obtained with blood draws after dose 12 (11–12 h).

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BMC Clinical Pharmacology

ISSN: 1472-6904