Table 5 Biological coefficients of variation (CV) of morphine, morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G) serum concentrations during four consecutive days of oral or subcutaneous morphine treatment. All values are given as median and range.
Biological coefficient of variation % | ||
|---|---|---|
Oral morphine | Subcutaneous morphine | |
Morphine | 46 (13–103) | 10 (0–36) |
M6G | 25 (1–72) | 13 (2–40) |
M3G | 18 (0–57) | 9 (0–34) |