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Figure 6 | BMC Clinical Pharmacology

Figure 6

From: Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood

Figure 6

Perfusion rate dependence (F A ) of the model fits to the experimental adipose concentration measurements (solid circles) for tetrachlorodibenzo-p-dioxin (TCDD, Wang et. al. [5]) and tetrabromodibenzo-p-dioxin (TBDD, Kedderis et. al. [35]). The red line is the predicted fit using the optimal value of FA for that solute and the green line is the fit using the FA of the other solute. For the green lines, the value of the adipose/blood partition (K) was adjusted to approximately fit the last time point.

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BMC Clinical Pharmacology

ISSN: 1472-6904